Effectiveness and safety of long-term treatment with sulfonylureas in patients with neonatal diabetes due to KCNJ11 mutations: an international cohort study

BACKGROUND: KCNJ11 mutations cause permanent neonatal diabetes through pancreatic ATP-sensitive potassium channel activation. 90% of patients successfully transfer from insulin to oral sulfonylureas with excellent initial glycaemic control; however, whether this control is maintained in the long ter...

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Udgivet i:Lancet Diabetes Endocrinol
Main Authors: Bowman, Pamela, Sulen, Åsta, Barbetti, Fabrizio, Beltrand, Jacques, Svalastoga, Pernille, Codner, Ethel, Tessmann, Ellen H, Juliusson, Petur B, Skrivarhaug, Torild, Pearson, Ewan R, Flanagan, Sarah E, Babiker, Tarig, Thomas, Nicholas J, Shepherd, Maggie H, Ellard, Sian, Klimes, Iwar, Szopa, Magdalena, Polak, Michel, Iafusco, Dario, Hattersley, Andrew T, Njølstad, Pål R
Format: Artigo
Sprog:Inglês
Udgivet: The Lancet, Diabetes & Endocrinology 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058077/
https://ncbi.nlm.nih.gov/pubmed/29880308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-8587(18)30106-2
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