Whole-genome sequencing reveals new insights into age-related hearing loss: cumulative effects, pleiotropy and the role of selection

Age-related hearing loss (ARHL) is the most common sensory disorder in the elderly. Although not directly life threatening, it contributes to loss of autonomy and is associated with anxiety, depression and cognitive decline. To search for genetic risk factors underlying ARHL, a large whole-genome se...

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Gepubliceerd in:Eur J Hum Genet
Hoofdauteurs: Vuckovic, Dragana, Mezzavilla, Massimo, Cocca, Massimiliano, Morgan, Anna, Brumat, Marco, Catamo, Eulalia, Concas, Maria Pina, Biino, Ginevra, Franzè, Annamaria, Ambrosetti, Umberto, Pirastu, Mario, Gasparini, Paolo, Girotto, Giorgia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer International Publishing 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057993/
https://ncbi.nlm.nih.gov/pubmed/29725052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-018-0126-2
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