Tissue non-specific alkaline phosphatase (TNAP) is required for MC3T3 osteoblast-mediated protection of acute myeloid leukemia cells from apoptosis

The bone marrow microenvironment harbors and protects leukemic cells from apoptosis-inducing agents via mechanisms that are incompletely understood. We previously showed SDF-1 (CXCL-12), a chemokine readily abundant within the bone marrow microenvironment, induces apoptosis in acute myeloid leukemia...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: Sterner, Rosalie M., Kremer, Kimberly N., Dudakovic, Amel, Westendorf, Jennifer J., van Wijnen, Andre J., Hedin, Karen E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057831/
https://ncbi.nlm.nih.gov/pubmed/29914885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800174
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