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Conflicting roles of 20-HETE in hypertension and renal end organ damage
20-HETE is a cytochrome P450-derived metabolite of arachidonic acid that has both pro- and anti-hypertensive actions that result from modulation of vascular and kidney function. In the vasculature, 20-HETE sensitizes vascular smooth muscle cells to constrictor stimuli and increases myogenic tone. By...
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| Опубликовано в: : | Eur J Pharmacol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6057804/ https://ncbi.nlm.nih.gov/pubmed/29886242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2018.06.010 |
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