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Mild therapeutic hypothermia protects against cerebral ischemia/reperfusion injury by inhibiting miR-15b expression in rats

OBJECTIVE: Mild hypothermia has a protective effect on ischemic stroke, but the mechanisms remain elusive. Here, we investigated microRNA (miRNA) profiles and the specific role of miRNAs in ischemic stroke treated with mild hypothermia. MATERIALS AND METHODS: Male adult Sprague Dawley rats were subj...

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Detalhes bibliográficos
Publicado no:Brain Circ
Main Authors: Liu, Xiangrong, Wu, Di, Wen, Shaohong, Zhao, Shunying, Xia, Ao, Li, Fang, Ji, Xunming
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057705/
https://ncbi.nlm.nih.gov/pubmed/30276328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/bc.bc_15_17
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