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Differential modes of activation define orphan subclasses within the steroid/thyroid receptor superfamily

We report that three orphan receptors, hERRl, hERR2, and hTR2, members of the steroid/thyroid receptor (SR/TR) superfamily, can be activated by different ligand-independent pathways. hERRl and hERR2 exhibit constitutive activity in the absence of exogenously added ligands. Furthermore, this constitu...

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Detalhes bibliográficos
Publicado no:Gene Expr
Main Authors: Lydon, John P., Power, Ronan F., Conneely, Orla M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057375/
https://ncbi.nlm.nih.gov/pubmed/1450665
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