Human alveolar epithelial cells type II are capable of TGFβ-dependent epithelial-mesenchymal-transition and collagen-synthesis

BACKGROUND: The origin of collagen-producing cells in lung fibrosis is unclear. The involvement of embryonic signaling pathways has been acknowledged and trans-differentiation of epithelial cells is discussed critically. The work presented here investigates the role of TGFB in cytoskeleton remodelin...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Goldmann, Torsten, Zissel, Gernot, Watz, Henrik, Drömann, Daniel, Reck, Martin, Kugler, Christian, Rabe, Klaus F., Marwitz, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056940/
https://ncbi.nlm.nih.gov/pubmed/30041633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0841-9
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