When Bacterial Culture Fails, Metagenomics Can Help: A Case of Chronic Hepatic Brucelloma Assessed by Next-Generation Sequencing

Here, we sequenced DNA extracted from a necrotic hepatic lesion from a patient with suspected chronic hepatic brucelloma but negative culture results. Although most of the taxonomically classified sequencing reads corresponded to human genome sequences, our data suggest that whole-metagenome shotgun...

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Vydáno v:Front Microbiol
Hlavní autoři: Lazarevic, Vladimir, Gaïa, Nadia, Girard, Myriam, Leo, Stefano, Cherkaoui, Abdessalam, Renzi, Gesuele, Emonet, Stéphane, Jamme, Sharon, Ruppé, Etienne, Vijgen, Sandrine, Rubbia-Brandt, Laura, Toso, Christian, Schrenzel, Jacques
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056729/
https://ncbi.nlm.nih.gov/pubmed/30065706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01566
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