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Landscape of CDKN1B Mutations in Luminal Breast Cancer and Other Hormone-Driven Human Tumors
The CDKN1B gene encodes for the p27(Kip1) protein, firstly characterized as a cyclin dependent kinase (CDK)-inhibitor. Germline CDKN1B pathogenic variants have been described in hereditary tumors, such as multiple endocrine neoplasia (MEN)-like syndromes and familial prostate cancer. Despite its cen...
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| Pubblicato in: | Front Endocrinol (Lausanne) |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6056726/ https://ncbi.nlm.nih.gov/pubmed/30065701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00393 |
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