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Mitochondrial DNA replication in mammalian cells: overview of the pathway
Mammalian mitochondria contain multiple copies of a circular, double-stranded DNA genome and a dedicated DNA replication machinery is required for its maintenance. Many disease-causing mutations affect mitochondrial replication factors and a detailed understanding of the replication process may help...
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| Published in: | Essays Biochem |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Portland Press Ltd.
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6056714/ https://ncbi.nlm.nih.gov/pubmed/29880722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/EBC20170100 |
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