Oxytocin Relieves Neuropathic Pain Through GABA Release and Presynaptic TRPV1 Inhibition in Spinal Cord

Objective: Oxytocin (OT) is synthesized within the paraventricular nucleus and supraoptic nucleus of the hypothalamus. In addition to its role in uterine contraction, OT plays an important antinociceptive role; however, the underlying molecular mechanisms of antinociceptive role of OT remain elusive...

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Veröffentlicht in:Front Mol Neurosci
Hauptverfasser: Sun, Wuping, Zhou, Qian, Ba, Xiyuan, Feng, Xiaojin, Hu, Xuexue, Cheng, Xiaoe, Liu, Tao, Guo, Jing, Xiao, Lizu, Jiang, Jin, Xiong, Donglin, Hao, Yue, Chen, Zixian, Jiang, Changyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056657/
https://ncbi.nlm.nih.gov/pubmed/30065629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00248
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