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Exposure to galactic cosmic radiation compromises DNA repair and increases the potential for oncogenic chromosomal rearrangement in bronchial epithelial cells

Participants in deep space missions face protracted exposure to galactic cosmic radiation (GCR). In this setting, lung cancer is a significant component of the overall risk of radiation-exposure induced death. Here we investigate persistent effects of GCR exposure on DNA repair capacity in lung-deri...

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Publicat a:Sci Rep
Autors principals: Li, Z., Jella, K. K., Jaafar, L., Li, S., Park, S., Story, M. D., Wang, H., Wang, Y., Dynan, W. S.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056477/
https://ncbi.nlm.nih.gov/pubmed/30038404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29350-5
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