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IL-7 treatment supports CD8+ MAIT cell restoration in HIV-1 infected patients on ART

Chronic HIV-1 infection is associated with lower frequencies and functional impairment of mucosa-associated invariant T (MAIT) cells. We evaluated IL-7 treatment to restore MAIT cells in peripheral blood of chronically HIV-1 infected individuals on ART. IL-7 led to increased relative and absolute le...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:AIDS
Prif Awduron: Sortino, Ornella, Richards, Elizabeth, Dias, Joana, Leeansyah, Edwin, Sandberg, Johan K., Sereti, Irini
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056340/
https://ncbi.nlm.nih.gov/pubmed/29543654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001760
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