Small Molecule Tyrosine Kinase Inhibitor Nintedanib Reduces Development of Cardiac Allograft Vasculopathy in Murine Aortic Allografts

BACKGROUND: Nintedanib is a small molecule tyrosine kinase inhibitor that blocks the action of the platelet-derived growth factor receptor (PDGFR), the vascular endothelial growth factor receptor (VEGFR) and the fibroblast growth factor receptor. All of these receptors have been shown to be involved...

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Detalhes bibliográficos
Publicado no:Transplant Direct
Main Authors: Gocht, Annika, Spriewald, Bernd, Distler, Jörg H.W., Ramsperger-Gleixner, Martina, Ensminger, Stephan M., Weyand, Michael, Heim, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
Assuntos:
Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056280/
https://ncbi.nlm.nih.gov/pubmed/30046657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000000804
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