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Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner

Neural crest progenitors are specified through the modulation of several signaling pathways, among which the activation of Wnt/β-catenin signaling by Wnt8 is especially critical. Glycoproteins of the Dickkopf (Dkk) family are important modulators of Wnt signaling acting primarily as Wnt antagonists....

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Devotta, Arun, Hong, Chang-Soo, Saint-Jeannet, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056231/
https://ncbi.nlm.nih.gov/pubmed/30035713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.34404
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