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Function of a membrane-embedded domain evolutionarily multiplied in the GPI lipid anchor pathway proteins PIG-B, PIG-M, PIG-U, PIG-W, PIG-V, and PIG-Z

Distant homology relationships among proteins with many transmembrane regions (TMs) are difficult to detect as they are clouded by the TMs’ hydrophobic compositional bias and mutational divergence in connecting loops. In the case of several GPI lipid anchor biosynthesis pathway components, the hidde...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Eisenhaber, Birgit, Sinha, Swati, Wong, Wing-Cheong, Eisenhaber, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056205/
https://ncbi.nlm.nih.gov/pubmed/29764287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1456294
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