Investigation of epigenetic regulatory networks associated with autism spectrum disorder (ASD) by integrated global LINE-1 methylation and gene expression profiling analyses

BACKGROUND: The exact cause and mechanisms underlying the pathobiology of autism spectrum disorder (ASD) remain unclear. Dysregulation of long interspersed element-1 (LINE-1) has been reported in the brains of ASD-like mutant mice and ASD brain tissues. However, the role and methylation of LINE-1 in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Tangsuwansri, Chayanin, Saeliw, Thanit, Thongkorn, Surangrat, Chonchaiya, Weerasak, Suphapeetiporn, Kanya, Mutirangura, Apiwat, Tencomnao, Tewin, Hu, Valerie Wailin, Sarachana, Tewarit
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056057/
https://ncbi.nlm.nih.gov/pubmed/30036398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201071
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