Neuronal Surface and Glutamic Acid Decarboxylase Autoantibodies in Nonparaneoplastic Stiff Person Syndrome

IMPORTANCE: High titers of autoantibodies to glutamic acid decarboxylase (GAD) are well documented in association with stiff person syndrome (SPS). Glutamic acid decarboxylase is the rate-limiting enzyme in the synthesis of γ-aminobutyric acid (GABA), and impaired function of GABAergic neurons has b...

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Publicado no:JAMA Neurol
Main Authors: Chang, Thashi, Alexopoulos, Haris, McMenamin, Mary, Carvajal-González, Alexander, Alexander, Sian K., Deacon, Robert, Erdelyi, Ferenc, Szabó, Gabor, Lang, Bethan, Blaes, Franz, Brown, Peter, Vincent, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055982/
https://ncbi.nlm.nih.gov/pubmed/23877118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.3499
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