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How to use prior knowledge and still give new data a chance?

A common challenge for the development of drugs in rare diseases and special populations, eg, paediatrics, is the small numbers of patients that can be recruited into clinical trials. Extrapolation can be used to support development and licensing in paediatrics through the structured integration of...

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Detalhes bibliográficos
Publicado no:Pharm Stat
Main Authors: Weber, Kristina, Hemmings, Rob, Koch, Armin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055870/
https://ncbi.nlm.nih.gov/pubmed/29667367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.1862
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