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Super analgesia of intrathecal morphine may be related to ABCB1 (MDR1) gene polymorphism

Intrathecal morphine provides superior analgesia and minimizes side effects with ~1/300th of the oral dose necessary to achieve this effect. The conversion ratios from oral route to intrathecal route vary greatly among individuals, and this may be related with polymorphisms of the ATP-binding casset...

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Dades bibliogràfiques
Publicat a:J Pain Res
Autors principals: Qin, Wangjun, Liu, Botao, Deng, Ang, Liu, Ying, Zhang, Xianglin, Zhang, Lei
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055837/
https://ncbi.nlm.nih.gov/pubmed/30050319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S156919
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