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Chemically controlled aggregation of pluripotent stem cells

Heterogeneity in pluripotent stem cell (PSC) aggregation leads to variability in mass transfer and signaling gradients between aggregates, which results in heterogeneous differentiation and therefore variability in product quality and yield. We have characterized a chemical‐based method to control a...

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Detalles Bibliográficos
Publicado en:Biotechnol Bioeng
Main Authors: Lipsitz, Yonatan Y., Tonge, Peter D., Zandstra, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055717/
https://ncbi.nlm.nih.gov/pubmed/29679475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26719
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