Molecular Cytogenetics Guides Massively Parallel Sequencing of a Radiation-Induced Chromosome Translocation in Human Cells

Chromosome rearrangements are large-scale structural variants that are recognized drivers of oncogenic events in cancers of all types. Cytogenetics allows for their rapid, genome-wide detection, but does not provide gene-level resolution. Massively parallel sequencing (MPS) promises DNA sequence-lev...

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Detalhes bibliográficos
Publicado no:Radiat Res
Main Authors: Cornforth, Michael N., Anur, Pavana, Wang, Nicholas, Robinson, Erin, Ray, F. Andrew, Bedford, Joel S., Loucas, Bradford D., Williams, Eli S., Peto, Myron, Spellman, Paul, Kollipara, Rahul, Kittler, Ralf, Gray, Joe W., Bailey, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055522/
https://ncbi.nlm.nih.gov/pubmed/29749794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR15053.1
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