Molecular Cytogenetics Guides Massively Parallel Sequencing of a Radiation-Induced Chromosome Translocation in Human Cells

Chromosome rearrangements are large-scale structural variants that are recognized drivers of oncogenic events in cancers of all types. Cytogenetics allows for their rapid, genome-wide detection, but does not provide gene-level resolution. Massively parallel sequencing (MPS) promises DNA sequence-lev...

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Détails bibliographiques
Publié dans:Radiat Res
Auteurs principaux: Cornforth, Michael N., Anur, Pavana, Wang, Nicholas, Robinson, Erin, Ray, F. Andrew, Bedford, Joel S., Loucas, Bradford D., Williams, Eli S., Peto, Myron, Spellman, Paul, Kollipara, Rahul, Kittler, Ralf, Gray, Joe W., Bailey, Susan M.
Format: Artigo
Langue:Inglês
Publié: 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055522/
https://ncbi.nlm.nih.gov/pubmed/29749794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR15053.1
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