Characterisation of tau in the human and rodent enteric nervous system under physiological conditions and in tauopathy

Tau is normally a highly soluble phosphoprotein found predominantly in neurons. Six different isoforms of tau are expressed in the adult human CNS. Under pathological conditions, phosphorylated tau aggregates are a defining feature of neurodegenerative disorders called tauopathies. Recent findings h...

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Publicado en:Acta Neuropathol Commun
Autores principales: Lionnet, Arthur, Wade, Matthew A., Corbillé, Anne-Gaëlle, Prigent, Alice, Paillusson, Sébastien, Tasselli, Maddalena, Gonzales, Jacques, Durieu, Emilie, Rolli-Derkinderen, Malvyne, Coron, Emmanuel, Duchalais, Emilie, Neunlist, Michel, Perkinton, Michael S., Hanger, Diane P., Noble, Wendy, Derkinderen, Pascal
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055332/
https://ncbi.nlm.nih.gov/pubmed/30037345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0568-3
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