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Serum exosomes mediate delivery of arginase 1 as a novel mechanism for endothelial dysfunction in diabetes

Exosomes, abundant in blood, deliver various molecules to recipient cells. Endothelial cells are directly exposed to circulating substances. However, how endothelial cells respond to serum exosomes (SExos) and the implications in diabetes-associated vasculopathy have never been explored. In the pres...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhang, Huina, Liu, Jian, Qu, Dan, Wang, Li, Wong, Chi Ming, Lau, Chi-Wai, Huang, Yuhong, Wang, Yi Fan, Huang, Huihui, Xia, Yin, Xiang, Li, Cai, Zongwei, Liu, Pingsheng, Wei, Yongxiang, Yao, Xiaoqiang, Ma, Ronald Ching Wan, Huang, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055191/
https://ncbi.nlm.nih.gov/pubmed/29967177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721521115
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