Nicotine Modulates Cognitive Function in D-Galactose-Induced Senescence in Mice

Here, we tested the claim that nicotine attenuates the signs of brain dysfunction in the model of brain aging induced by D-galactose (DGal) in mice. We administered nicotine at doses of 0.1, 0.5 and 1 mg/kg by the subcutaneous (s.c.) or at 0.1 mg/kg by the intranasal (i.n.) routes in mice that had r...

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Publicat a:Front Aging Neurosci
Autors principals: Majdi, Alireza, Sadigh-Eteghad, Saeed, Talebi, Mahnaz, Farajdokht, Fereshteh, Erfani, Marjan, Mahmoudi, Javad, Gjedde, Albert
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055060/
https://ncbi.nlm.nih.gov/pubmed/30061821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00194
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