Activating AMPK to Restore Tight Junction Assembly in Intestinal Epithelium and to Attenuate Experimental Colitis by Metformin

Adenosine monophosphate-activated protein kinase (AMPK), a crucial molecule in energy metabolism, is reported to play a potential role in gut epithelial differentiation and barrier function recently; however, its performance and mechanisms in the pathological process of inflammatory bowel diseases r...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Chen, Lu, Wang, Jie, You, Qian, He, Shuai, Meng, Qianqian, Gao, Jian, Wu, Xudong, Shen, Yan, Sun, Yang, Wu, Xuefeng, Xu, Qiang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054982/
https://ncbi.nlm.nih.gov/pubmed/30061832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00761
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