Efficacy and Safety Profile of Z-215 (Azeloprazole Sodium), a Proton Pump Inhibitor, Compared with Rabeprazole Sodium in Patients with Reflux Esophagitis: A Phase II, Multicenter, Randomized, Double-Blind, Comparative Study

BACKGROUND: The metabolism of many proton pump inhibitors is influenced by CYP2C19 genotype, which is a limitation of their use. OBJECTIVES: To determine the efficacy and safety profile of Z-215 (azeloprazole sodium) as initial treatment for reflux esophagitis (RE), dose response, and optimal dose c...

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Detalhes bibliográficos
Publicado no:Curr Ther Res Clin Exp
Main Authors: Kinoshita, Yoshikazu, Kusano, Motoyasu, Iwakiri, Katsuhiko, Fujishiro, Mitsuhiro, Tachikawa, Naoto, Haruma, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054772/
https://ncbi.nlm.nih.gov/pubmed/30038671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.curtheres.2018.03.004
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