Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism

Antibiotic-induced microbiome depletion (AIMD) has been used frequently to study the role of the gut microbiome in pathological conditions. However, unlike germ-free mice, the effects of AIMD on host metabolism remain incompletely understood. Here we show the effects of AIMD to elucidate its effects...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Zarrinpar, Amir, Chaix, Amandine, Xu, Zhenjiang Z., Chang, Max W., Marotz, Clarisse A., Saghatelian, Alan, Knight, Rob, Panda, Satchidananda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054678/
https://ncbi.nlm.nih.gov/pubmed/30030441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05336-9
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