A blockade of PI3Kγ signaling effectively mitigates angiotensin II-induced renal injury and fibrosis in a mouse model

Chronic kidney disease (CKD) poses a formidable challenge for public healthcare worldwide as vast majority of patients with CKD are also at risk of accelerated cardiovascular disease and death. Renal fibrosis is the common manifestation of CKD that usually leads to end-stage renal disease although t...

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Publicado no:Sci Rep
Main Authors: Yu, Xinyi, Xia, Yunfeng, Zeng, Liyi, Zhang, Xi, Chen, Liqun, Yan, Shujuan, Zhang, Ruyi, Zhao, Chen, Zeng, Zongyue, Shu, Yi, Huang, Shifeng, Lei, Jiayan, Yuan, Chengfu, Zhang, Linghuan, Feng, Yixiao, Liu, Wei, Huang, Bo, Zhang, Bo, Luo, Wenping, Wang, Xi, Zhang, Hongmei, Haydon, Rex C., Luu, Hue H., He, Tong-Chuan, Gan, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054654/
https://ncbi.nlm.nih.gov/pubmed/30030497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29417-3
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