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Radical chain repair: The hydroalkylation of polysubstituted unactivated alkenes

The concept of repair is widely used by nature to heal molecules such as proteins, lipids, sugars, and DNA that are damaged by hydrogen atom abstraction resulting from oxidative stress. We show that this strategy, rather undocumented in the field of synthetic organic chemistry, can be used in a radi...

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Publicat a:Sci Adv
Autors principals: Povie, Guillaume, Suravarapu, Sankar Rao, Bircher, Martin Peter, Mojzes, Melinda Meyer, Rieder, Samuel, Renaud, Philippe
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054511/
https://ncbi.nlm.nih.gov/pubmed/30035230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aat6031
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