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Efficacy of N-carbamoyl-L-glutamic acid for the treatment of inherited metabolic disorders

INTRODUCTION: N-carbamoyl-L-glutamic acid (NCG) is a synthetic analogue of N-acetyl glutamate (NAG) that works effectively as a cofactor for carbamoyl phosphate synthase 1 and enhances ureagenesis by activating the urea cycle. NCG (brand name, Carbaglu) was recently approved by the United States Foo...

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Detalhes bibliográficos
Publicado no:Expert Rev Endocrinol Metab
Main Authors: Chapel-Crespo, Cristel C., Diaz, George A., Oishi, Kimihiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054484/
https://ncbi.nlm.nih.gov/pubmed/30034506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17446651.2016.1239526
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