Human immune cell engraftment does not alter development of severe acute Rift Valley fever in mice

Rift Valley fever (RVF) in humans is usually mild, but, in a subset of cases, can progress to severe hepatic and neurological disease. Rodent models of RVF generally develop acute severe clinical disease. Here, we inoculated humanized NSG-SGM3 mice with Rift Valley fever virus (RVFV) to investigate...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Spengler, Jessica R., McElroy, Anita K., Harmon, Jessica R., Coleman-McCray, JoAnn D., Welch, Stephen R., Keck, James G., Nichol, Stuart T., Spiropoulou, Christina F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054394/
https://ncbi.nlm.nih.gov/pubmed/30028878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201104
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