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Acid Stimulation of the Citrate Transporter NaDC-1 Requires Pyk2 and ERK1/2 Signaling Pathways
Background Urine citrate is reabsorbed exclusively along the renal proximal tubule via the apical Na(+)-dicarboxylate cotransporter NaDC-1. We previously showed that an acid load in vivo and media acidification in vitro increase NaDC-1 activity through endothelin-1 (ET-1)/endothelin B (ET(B)) signal...
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| Publié dans: | J Am Soc Nephrol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Nephrology
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6054333/ https://ncbi.nlm.nih.gov/pubmed/29678998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017121268 |
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