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Sarpagan bridge enzyme has substrate-controlled cyclization and aromatization modes
Cyclization reactions that create complex polycyclic scaffolds are hallmarks of alkaloid biosynthetic pathways. We present the discovery of three homologous cytochromes P450 from three monoterpene indole alkaloid-producing plants (Rauwolfia serpentina, Gelsemium sempervirens and Catharanthus roseus)...
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| Publicado no: | Nat Chem Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6054303/ https://ncbi.nlm.nih.gov/pubmed/29942076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0078-4 |
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