Preventive effects of crocin on neuronal damages induced by D-galactose through AGEs and oxidative stress in human neuroblastoma cells (SH-SY5Y)

OBJECTIVE: D-galactose (D-gal) is well-known agent to induce aging process. In the present study, we selected crocin, the main constituent of Crocus sativus L. (saffron), against D-gal-induced cytotoxicity in human neuroblastoma SH-SY5Y cells. METHODS: Pretreated cells with crocin (25–500 μM, 24 h)...

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Bibliographic Details
Published in:J Pharmacopuncture
Main Authors: Heidari, Somaye, Mehri, Soghra, Shariaty, Vahidesadat, Hosseinzadeh, Hossein
Format: Artigo
Language:Inglês
Published: The Korean Pharmacopuncture Institute (KPI) 2018
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054079/
https://ncbi.nlm.nih.gov/pubmed/30151301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3831/KPI.2018.21.003
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