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Applications of the class II lanthipeptide protease LicP for sequence-specific, traceless peptide bond cleavage

The final step of lanthipeptide biosynthesis involves the removal of leader peptides by dedicated proteases. In vitro characterization of LicP, a class II LanP protease involved in the biosynthesis of the lantibiotic lichenicidin, revealed a self-cleavage step that removes 100 amino acids from the N...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Tang, Weixin, Dong, Shi-Hui, Repka, Lindsay M., He, Chang, Nair, Satish K., van der Donk, Wilfred A.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054071/
https://ncbi.nlm.nih.gov/pubmed/30090246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc02329g
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