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Lab on a single microbead: an ultrasensitive detection strategy enabling microRNA analysis at the single-molecule level

Detection of a single nucleic acid molecule is of great significance for both fundamental biochemistry studies and clinical diagnostics. By using microRNA (miRNA) as a model target, herein, we have developed a single-microbead-based sensing (SMBS) platform, which simply enables the detection of miRN...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Zhang, Xiaobo, Liu, Chenghui, Sun, Lingbo, Duan, Xinrui, Li, Zhengping
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054045/
https://ncbi.nlm.nih.gov/pubmed/30090237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc02641e
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