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Two distinct ontogenies confer heterogeneity to mouse brain microglia
Hoxb8 mutant mice show compulsive behavior similar to trichotillomania, a human obsessive-compulsive-spectrum disorder. The only Hoxb8 lineage-labeled cells in the brains of mice are microglia, suggesting that defective Hoxb8 microglia caused the disorder. What is the source of the Hoxb8 microglia?...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Development |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The Company of Biologists Ltd
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6053660/ https://ncbi.nlm.nih.gov/pubmed/29973370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.152306 |
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