Sox30 initiates transcription of haploid genes during late meiosis and spermiogenesis in mouse testes

Transcription factors of the Sox protein family contain a DNA-binding HMG box and are key regulators of progenitor cell fate. Here, we report that expression of Sox30 is restricted to meiotic spermatocytes and postmeiotic haploids. Sox30 mutant males are sterile owing to spermiogenic arrest at the e...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Bai, Shun, Fu, Kaiqiang, Yin, Huiqi, Cui, Yiqiang, Yue, Qiuling, Li, Wenbo, Cheng, Le, Tan, Huanhuan, Liu, Xiaofei, Guo, Yueshuai, Zhang, Yingwen, Xie, Jie, He, Wenxiu, Wang, Yuanyuan, Feng, Hua, Xin, Changpeng, Zhang, Jinwen, Lin, Mingyan, Shen, Bin, Sun, Zheng, Guo, Xuejiang, Zheng, Ke, Ye, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053656/
https://ncbi.nlm.nih.gov/pubmed/29866902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.164855
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