Small molecule activator of Nm23/NDPK as an inhibitor of metastasis

Nm23-H1/NDPK-A is a tumor metastasis suppressor having NDP kinase (NDPK) activity. Nm23-H1 is positively associated with prolonged disease-free survival and good prognosis of cancer patients. Approaches to increasing the cellular levels of Nm23-H1 therefore have significance in the therapy of metast...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Lee, Jae-Jin, Kim, Hwang Suk, Lee, Ji-Sun, Park, Jimin, Shin, Sang Chul, Song, Soonwha, Lee, Eunsun, Choi, Jung-Eun, Suh, Ji-Wan, Lee, Hongsoo, Kim, Eunice EunKyeong, Seo, Eun Kyoung, Shin, Dong Hae, Lee, Ho-Young, Lee, Hee-Yoon, Lee, Kong-Joo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053448/
https://ncbi.nlm.nih.gov/pubmed/30026594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29101-6
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