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Substitution of linoleic acid with α-linolenic acid or long chain n-3 polyunsaturated fatty acid prevents Western diet induced nonalcoholic steatohepatitis

Imbalance in the n-6 polyunsaturated fatty acids (PUFA) and n-3 PUFA in the Western diet may increase the risk of nonalcoholic fatty liver disease (NAFLD). This study investigates the impact of substitution of linoleic acid with α-linolenic acid (ALA) or long chain (LC) n-3 PUFA and hence decreasing...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Jeyapal, Sugeedha, Kona, Suryam Reddy, Mullapudi, Surekha Venkata, Putcha, Uday Kumar, Gurumurthy, Puvaneswari, Ibrahim, Ahamed
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053361/
https://ncbi.nlm.nih.gov/pubmed/30026586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29222-y
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