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Missing single nucleotide polymorphisms in Genetic Risk Scores: A simulation study
Using a genetic risk score (GRS) to predict a phenotype in a target sample can be complicated by missing data on the single nucleotide polymorphisms (SNPs) that comprise the GRS. This is usually addressed by imputation, omission of the SNPs or by replacing the missing SNPs with proxy SNPs. To assess...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6053141/ https://ncbi.nlm.nih.gov/pubmed/30024900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200630 |
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