Synthetic beta cells for fusion-mediated dynamic insulin secretion

Generating artificial pancreatic beta cells by using synthetic materials to mimic glucose-responsive insulin secretion in a robust manner holds promise for improving clinical outcomes in people with diabetes. Here, we describe the construction of artificial beta cells (AβCs) with a multicompartmenta...

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Udgivet i:Nat Chem Biol
Main Authors: Chen, Zhaowei, Wang, Jinqiang, Sun, Wujin, Archibong, Edikan, Kahkoska, Anna R, Zhang, Xudong, Lu, Yue, Ligler, Frances S, Buse, John B, Gu, Zhen
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053053/
https://ncbi.nlm.nih.gov/pubmed/29083418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2511
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