Soluble CD83 Alleviates Experimental Autoimmune Uveitis by Inhibiting Filamentous Actin-Dependent Calcium Release in Dendritic Cells

Soluble CD83 (sCD83) is the extracellular domain of the membrane-bound CD83 molecule, and known for its immunoregulatory functions. Whether and how sCD83 participates in the pathogenesis of uveitis, a serious inflammatory disease of the eye that can cause visual disability and blindness, is unknown....

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Pubblicato in:Front Immunol
Autori principali: Lin, Wei, Buscher, Konrad, Wang, Beibei, Fan, Zhichao, Song, Nannan, Li, Peng, Yue, Yingying, Li, Bingqing, Li, Cuiling, Bi, Hongsheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052908/
https://ncbi.nlm.nih.gov/pubmed/30050530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01567
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