Immune Cell Profiling During Switching from Natalizumab to Fingolimod Reveals Differential Effects on Systemic Immune-Regulatory Networks and on Trafficking of Non-T Cell Populations into the Cerebrospinal Fluid—Results from the ToFingo Successor Study

Leukocyte sequestration is an established therapeutic concept in multiple sclerosis (MS) as represented by the trafficking drugs natalizumab (NAT) and fingolimod (FTY). However, the precise consequences of targeting immune cell trafficking for immunoregulatory network functions are only incompletely...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Immunol
Prif Awduron: Lohmann, Lisa, Janoschka, Claudia, Schulte-Mecklenbeck, Andreas, Klinsing, Svenja, Kirstein, Lucienne, Hanning, Uta, Wirth, Timo, Schneider-Hohendorf, Tilman, Schwab, Nicholas, Gross, Catharina C., Eveslage, Maria, Meuth, Sven G., Wiendl, Heinz, Klotz, Luisa
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2018
Pynciau:
Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052886/
https://ncbi.nlm.nih.gov/pubmed/30050529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01560
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