Preferential use of Siglec-1 or Siglec-10 by type 1 and type 2 PRRSV strains to infect PK15(S1–CD163) and PK15(S10–CD163) cells

Cellular entry mediators define whether the cell is permissive to PRRSV infection. Porcine sialoadhesin (pSn, Siglec-1) and CD163 are main entry mediators facilitating infection of porcine macrophages by PRRSV. Recently, Siglec-10 was demonstrated to be an alternative receptor for PRRSV. To examine...

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Detalhes bibliográficos
Publicado no:Vet Res
Main Authors: Xie, Jiexiong, Christiaens, Isaura, Yang, Bo, Trus, Ivan, Devriendt, Bert, Cui, Tingting, Wei, Ruifang, Nauwynck, Hans J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052533/
https://ncbi.nlm.nih.gov/pubmed/30021620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-018-0569-z
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