Human electronegative LDL induces mitochondrial dysfunction and premature senescence of vascular cells in vivo

Dysregulation of plasma lipids is associated with age‐related cardiovascular diseases. L5, the most electronegative subfraction of chromatographically resolved low‐density lipoprotein (LDL), induces endothelial dysfunction, whereas the least electronegative subfraction, L1, does not. In this study,...

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Vydáno v:Aging Cell
Hlavní autoři: Wang, Yu‐Chen, Lee, An‐Sheng, Lu, Long‐Sheng, Ke, Liang‐Yin, Chen, Wei‐Yu, Dong, Jian‐Wen, Lu, Jonathan, Chen, Zhenping, Chu, Chih‐Sheng, Chan, Hua‐Chen, Kuzan, Taha Y., Tsai, Ming‐Hsien, Hsu, Wen‐Li, Dixon, Richard A. F., Sawamura, Tatsuya, Chang, Kuan‐Cheng, Chen, Chu‐Huang
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052487/
https://ncbi.nlm.nih.gov/pubmed/29923368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12792
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