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Human electronegative LDL induces mitochondrial dysfunction and premature senescence of vascular cells in vivo

Dysregulation of plasma lipids is associated with age‐related cardiovascular diseases. L5, the most electronegative subfraction of chromatographically resolved low‐density lipoprotein (LDL), induces endothelial dysfunction, whereas the least electronegative subfraction, L1, does not. In this study,...

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Bibliografiska uppgifter
I publikationen:Aging Cell
Huvudupphovsmän: Wang, Yu‐Chen, Lee, An‐Sheng, Lu, Long‐Sheng, Ke, Liang‐Yin, Chen, Wei‐Yu, Dong, Jian‐Wen, Lu, Jonathan, Chen, Zhenping, Chu, Chih‐Sheng, Chan, Hua‐Chen, Kuzan, Taha Y., Tsai, Ming‐Hsien, Hsu, Wen‐Li, Dixon, Richard A. F., Sawamura, Tatsuya, Chang, Kuan‐Cheng, Chen, Chu‐Huang
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2018
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052487/
https://ncbi.nlm.nih.gov/pubmed/29923368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12792
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