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Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging

Inability to preserve proteostasis with age contributes to the gradual loss of function that characterizes old organisms. Defective autophagy, a component of the proteostasis network for delivery and degradation of intracellular materials in lysosomes, has been described in multiple old organisms, w...

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Bibliografiska uppgifter
I publikationen:Aging Cell
Huvudupphovsmän: Bejarano, Eloy, Murray, John W., Wang, Xintao, Pampliega, Olatz, Yin, David, Patel, Bindi, Yuste, Andrea, Wolkoff, Allan W., Cuervo, Ana Maria
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052466/
https://ncbi.nlm.nih.gov/pubmed/29845728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12777
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