Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers

Ischemia/reperfusion (I/R) injury is a causative factor contributing to morbidity and mortality during liver resection and transplantation. Livers from elderly patients have a poorer recovery from these surgeries, indicating reduced reparative capacity with aging. Mechanisms underlying this age‐medi...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Chun, Sung Kook, Lee, Sooyeon, Flores‐Toro, Joseph, U, Rebecca Y., Yang, Ming‐Jim, Go, Kristina L., Biel, Thomas G., Miney, Catherine E., Pierre Louis, Schiley, Law, Brian K., Law, Mary E., Thomas, Elizabeth M., Behrns, Kevin E., Leeuwenburgh, Christiaan, Kim, Jae‐Sung
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052398/
https://ncbi.nlm.nih.gov/pubmed/29774638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12761
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