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Modifying the Lantibiotic Mutacin 1140 for Increased Yield, Activity, and Stability
Mutacin 1140 belongs to the epidermin family of type AI lantibiotics. This family has a broad spectrum of activity against Gram-positive bacteria. The binding of mutacin 1140 to lipid II leads to the inhibition of cell wall synthesis. Pharmacokinetic experiments with type AI lantibiotics are general...
Shranjeno v:
| izdano v: | Appl Environ Microbiol |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6052277/ https://ncbi.nlm.nih.gov/pubmed/29776930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00830-18 |
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