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Modifying the Lantibiotic Mutacin 1140 for Increased Yield, Activity, and Stability

Mutacin 1140 belongs to the epidermin family of type AI lantibiotics. This family has a broad spectrum of activity against Gram-positive bacteria. The binding of mutacin 1140 to lipid II leads to the inhibition of cell wall synthesis. Pharmacokinetic experiments with type AI lantibiotics are general...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Appl Environ Microbiol
Prif Awduron: Geng, Mengxin, Smith, Leif
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052277/
https://ncbi.nlm.nih.gov/pubmed/29776930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00830-18
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